The Hemp Connection [Search results for oxidation] 

I recently started to tell a good friend about the antioxidant power of turmeric. He stopped me midsentence.

"What is it with all this antioxidant stuff? First it was pomegranates. Then it was Mongolian gojis. It's something different every day."

(Insert big sigh and eye roll here.)

"Can you even tell me what an antioxidant looks like?"

My friend's reaction verified something I've sensed for awhile now. In our quest to show how much we know about antioxidants, we've thrown long words and catch phrases at the public, to the point where the concept has become nothing more than hype.

It's not long after any concept hits"hype mode" that it becomes passe. And being passe is absolutely not what the average antioxidant should be, to ANYONE.

So, I'd like to answer my friend's question. My answer is somewhat long, but I will do my best to encourage him--and you--to see past the hype that's been flung at all those innocent pomegranates and beets and Indian curries!

Here are ten important things to know about antioxidants.

1. AN ANTIOXIDANT IS LIKE RUSTPROOF FOR YOUR BODY. Oxidation is the natural process of something breaking down over time. On your car, oxidation looks like rust. Oxidation in humans isn't much different; it's somewhat of a biological rusting out process. So an antioxidant, really, is human rustproofing.

2. AN ANTIOXIDANT SLOWS DOWN AGING. This is primarily a blog for women with PCOS. What does aging have to do with that? PCOS is a disease of inflammation, and inflammation is an aging process. If you stand back and look at the big picture, a lot of the symptoms of PCOS are actually indications of an accelerated aging process--arthritis, forgetfulness, poor sleep, diabetes at an early age, premature menopause--I am struck at how many of my clients really present as old people in young peoples' bodies. Just as there really is no cure for the wear and tear on the body of a car that works better than prevention, PCOS needs preventive action. It's about choosing food, activity and lifestyle behaviors that make it easier for your body to stay young. It IS possible to reverse some aging, but it's a whole lot easier to prevent aging before it happens. Making good antioxidant choices every day is an important part of your personal rustproofing plan (PRP).

3. DON'T JUDGE AN ANTIOXIDANT BY ITS SCRABBLE SCORE. This one drives me nuts. Nutritionists tend to be extremely detail oriented, and they seem to have adopted this compulsion to throw dozens of new long words at the public. I am equally as nerdy when it comes to biochemistry, but there is a place for those words. If seeing them in an article isn't inspiring you to put some new and different foods on your shopping list, what's the point?

I don't believe in dumbing down the public, but I have to admit, much of what I read has MY eyes glazing over because how the word was spelled or pronounced was apparently more important to the author than what's in it for me to care.

If you're adding a few beets at the salad bar or learning to cook Indian curries, that's what matters. The chemicals will help you to be healthier, whether or not you can spell or pronounce them.

4. THE BEST ANTIOXIDANTS ARE FOUND IN THEIR ORIGINAL PACKAGING. I graduated from college in 1982, and there were only a handful of antioxidants to learn about at the most. Back then (I guess you could say the nutritional dark ages!) we learned mostly about vitamins and minerals. Many of the compounds we knew about, were extracted and sold as"complete nutritional replacements". Of course, the definition of"complete" was based on our limited knowledge of what food actually contains. They weren't really complete because they did not contain the antioxidant compounds we didn't even know about!

That, for me, was a huge lesson learned, about how much of an expert I can truly be in this field. There will always be things I don't know, and need to know, and my responsibility as a health educator is to be as complete in talking about what I don't know as I do about what I do know.

Therefore, my advice when it comes to antioxidants and supplements, is not to focus on what the most important, most perfect antioxidant might be, then to extract it and consume it in large quantities. Rather, look for opportunities to eat whole foods that are as close to the ground and/or tree when you consume them. The more something is sliced, diced, extracted, powdered, concentrated, the less like nature it is.

Remember, whole is best. There may be important nutritional compounds we have yet to learn about that aren't in those expensive antioxidant supplements.

5. ANTIOXIDANTS ARE COLORFUL CHARACTERS. Your plate needs a variety of colors if it's also going to contain antioxidants. I created this graphic last summer to illustrate the concept. If you're eating lots of reds and blues, and are judicious about which white foods you choose, that's a good start. But remember the greens, yellows, and oranges, too! It's really not that hard to choose colorfully. A plate of food that contains a lot of colors is also attractive. Would you rather have a plate of white fish, cauliflower, and mashed potatoes, or a chicken salad packed with apples, walnuts, and spinach?

Eat patriotically--doesn't matter what country--if you put color on your plate, you can't go wrong.

6. ANTIOXIDANTS LOVE A GOOD PARTY! Antioxidants tend to be more effective in the presence of other antioxidants. In other words, you'll get more bang for your buck out of Compound A if you are also eating Compound B. That's why there is no such thing as the ultimate antioxidant. Just like you have less fun at a party if you act like a wallflower, your"health party" will be a whole lot more worthwhile if you introduce and mingle different compounds.

7. ANTIOXIDANTS LOVE THE GYM. Antioxidants have an interesting relationship with exercise. Exercise, because it raises metabolism, is actually an oxidative activity. However…when you exercise regularly, your body becomes more efficient at storing antioxidants for future use, and then mobilizing them to areas where exercise has raised your metabolism. To get the best advantage out of exercise, it's important to (1) not overexercise, but (2) exercise regularly, and (3) be sure the diet you eat on a regular basis is full of colorful foods.

8. ANTIOXIDANTS ARE HOMEBODIES. When fruits are picked early so they can be shipped to distant markets, they're not allowed to ripen and develop their fullest antioxidant potential. When fruits are processed so they can be stored and consumed through off-seasons, they lose antioxidant power. So while I love blueberries and I appreciate their antioxidant power, they are more of a summer treat for me. Since I live in Arizona, I try to eat lots of citrus in the winter, watermelon in the summer, and to use foods from other areas as occasional treats. Every locality has its specialties. Become familiar with what's in season in your area, and if you travel, experiment with local specialties. A Goji berry is definitely a powerful antioxidant tool, but you can be antioxidant friendly even if your plate was not partially picked by distant farmers on exotic hillsides. Some of your greatest antioxidant friends may be lurking just down the road at your local organic farm.

9. ANTIOXIDANTS SHOULD NOT BREAK YOUR BUDGET. When you eat seasonally, you should also save money. In fact, one of the easy way to know what fruits and vegetables are in season is to look for what is cheap! If you frequent your local farmer's market, what you see at the majority of the stands is likely the local seasonal offering. I like eating seasonally because foods move in and out of my menu and I don't get bored because I'm eating the same thing over and over again. Get to know how seasons affect food availability in your area, and plan menus around that. It is fun, not to mention tasty!

10. THE BEST ANTIOXIDANT OF ALL--IS A PROACTIVE LIFESTYLE. OK, here's a picture of an antioxidant. (A face only a molecule mother could love…) What it looks like isn't as important as what it does. An antioxidant keeps you healthy and young! Any choice you make that creates an imbalance--too much exercise and not enough rest, not enough sleep, an imbalanced diet, poor stress management--puts you at risk of antioxidant deficiency. If you're not making good lifestyle choices and assuming a supplement will absorb the imbalance, you're putting yourself at even greater risk. Be sure your diet has a lot of variety and color.

Even better, apply that mentality to the rest of your life.
--Create a social support network with a variety of personalities that encourage the best in you to come out, and who accept you for who you are without unrealistic expectations.
--Participate in a few different physical activities that allow muscles to rest while others work.
--Do things that make you laugh! (Yes, in a way, your favorite corny movie is an antioxidant!)
--Do something creative.

There are many kinds of antioxidants that have nothing to do with nutrition. Be sure your choices add up to move you in the direction of capitalizing on them, rather than putting you in a position where you need to supplement to reverse damage that didn't need to be done.

OK, good friend, I hope I answered your question and you made it to the end of this blog post without rolling those eyes again!

I recently started to tell a good friend about the antioxidant power of turmeric. He stopped me midsentence.

"What is it with all this antioxidant stuff? First it was pomegranates. Then it was Mongolian gojis. It's something different every day."

(Insert big sigh and eye roll here.)

"Can you even tell me what an antioxidant looks like?"

My friend's reaction verified something I've sensed for awhile now. In our quest to show how much we know about antioxidants, we've thrown long words and catch phrases at the public, to the point where the concept has become nothing more than hype.

It's not long after any concept hits"hype mode" that it becomes passe. And being passe is absolutely not what the average antioxidant should be, to ANYONE.

So, I'd like to answer my friend's question. My answer is somewhat long, but I will do my best to encourage him--and you--to see past the hype that's been flung at all those innocent pomegranates and beets and Indian curries!

Here are ten important things to know about antioxidants.

1. AN ANTIOXIDANT IS LIKE RUSTPROOF FOR YOUR BODY. Oxidation is the natural process of something breaking down over time. On your car, oxidation looks like rust. Oxidation in humans isn't much different; it's somewhat of a biological rusting out process. So an antioxidant, really, is human rustproofing.

2. AN ANTIOXIDANT SLOWS DOWN AGING. This is primarily a blog for women with PCOS. What does aging have to do with that? PCOS is a disease of inflammation, and inflammation is an aging process. If you stand back and look at the big picture, a lot of the symptoms of PCOS are actually indications of an accelerated aging process--arthritis, forgetfulness, poor sleep, diabetes at an early age, premature menopause--I am struck at how many of my clients really present as old people in young peoples' bodies. Just as there really is no cure for the wear and tear on the body of a car that works better than prevention, PCOS needs preventive action. It's about choosing food, activity and lifestyle behaviors that make it easier for your body to stay young. It IS possible to reverse some aging, but it's a whole lot easier to prevent aging before it happens. Making good antioxidant choices every day is an important part of your personal rustproofing plan (PRP).

3. DON'T JUDGE AN ANTIOXIDANT BY ITS SCRABBLE SCORE. This one drives me nuts. Nutritionists tend to be extremely detail oriented, and they seem to have adopted this compulsion to throw dozens of new long words at the public. I am equally as nerdy when it comes to biochemistry, but there is a place for those words. If seeing them in an article isn't inspiring you to put some new and different foods on your shopping list, what's the point?

I don't believe in dumbing down the public, but I have to admit, much of what I read has MY eyes glazing over because how the word was spelled or pronounced was apparently more important to the author than what's in it for me to care.

If you're adding a few beets at the salad bar or learning to cook Indian curries, that's what matters. The chemicals will help you to be healthier, whether or not you can spell or pronounce them.

4. THE BEST ANTIOXIDANTS ARE FOUND IN THEIR ORIGINAL PACKAGING. I graduated from college in 1982, and there were only a handful of antioxidants to learn about at the most. Back then (I guess you could say the nutritional dark ages!) we learned mostly about vitamins and minerals. Many of the compounds we knew about, were extracted and sold as"complete nutritional replacements". Of course, the definition of"complete" was based on our limited knowledge of what food actually contains. They weren't really complete because they did not contain the antioxidant compounds we didn't even know about!

That, for me, was a huge lesson learned, about how much of an expert I can truly be in this field. There will always be things I don't know, and need to know, and my responsibility as a health educator is to be as complete in talking about what I don't know as I do about what I do know.

Therefore, my advice when it comes to antioxidants and supplements, is not to focus on what the most important, most perfect antioxidant might be, then to extract it and consume it in large quantities. Rather, look for opportunities to eat whole foods that are as close to the ground and/or tree when you consume them. The more something is sliced, diced, extracted, powdered, concentrated, the less like nature it is.

Remember, whole is best. There may be important nutritional compounds we have yet to learn about that aren't in those expensive antioxidant supplements.

5. ANTIOXIDANTS ARE COLORFUL CHARACTERS. Your plate needs a variety of colors if it's also going to contain antioxidants. I created this graphic last summer to illustrate the concept. If you're eating lots of reds and blues, and are judicious about which white foods you choose, that's a good start. But remember the greens, yellows, and oranges, too! It's really not that hard to choose colorfully. A plate of food that contains a lot of colors is also attractive. Would you rather have a plate of white fish, cauliflower, and mashed potatoes, or a chicken salad packed with apples, walnuts, and spinach?

Eat patriotically--doesn't matter what country--if you put color on your plate, you can't go wrong.

6. ANTIOXIDANTS LOVE A GOOD PARTY! Antioxidants tend to be more effective in the presence of other antioxidants. In other words, you'll get more bang for your buck out of Compound A if you are also eating Compound B. That's why there is no such thing as the ultimate antioxidant. Just like you have less fun at a party if you act like a wallflower, your"health party" will be a whole lot more worthwhile if you introduce and mingle different compounds.

7. ANTIOXIDANTS LOVE THE GYM. Antioxidants have an interesting relationship with exercise. Exercise, because it raises metabolism, is actually an oxidative activity. However…when you exercise regularly, your body becomes more efficient at storing antioxidants for future use, and then mobilizing them to areas where exercise has raised your metabolism. To get the best advantage out of exercise, it's important to (1) not overexercise, but (2) exercise regularly, and (3) be sure the diet you eat on a regular basis is full of colorful foods.

8. ANTIOXIDANTS ARE HOMEBODIES. When fruits are picked early so they can be shipped to distant markets, they're not allowed to ripen and develop their fullest antioxidant potential. When fruits are processed so they can be stored and consumed through off-seasons, they lose antioxidant power. So while I love blueberries and I appreciate their antioxidant power, they are more of a summer treat for me. Since I live in Arizona, I try to eat lots of citrus in the winter, watermelon in the summer, and to use foods from other areas as occasional treats. Every locality has its specialties. Become familiar with what's in season in your area, and if you travel, experiment with local specialties. A Goji berry is definitely a powerful antioxidant tool, but you can be antioxidant friendly even if your plate was not partially picked by distant farmers on exotic hillsides. Some of your greatest antioxidant friends may be lurking just down the road at your local organic farm.

9. ANTIOXIDANTS SHOULD NOT BREAK YOUR BUDGET. When you eat seasonally, you should also save money. In fact, one of the easy way to know what fruits and vegetables are in season is to look for what is cheap! If you frequent your local farmer's market, what you see at the majority of the stands is likely the local seasonal offering. I like eating seasonally because foods move in and out of my menu and I don't get bored because I'm eating the same thing over and over again. Get to know how seasons affect food availability in your area, and plan menus around that. It is fun, not to mention tasty!

10. THE BEST ANTIOXIDANT OF ALL--IS A PROACTIVE LIFESTYLE. OK, here's a picture of an antioxidant. (A face only a molecule mother could love…) What it looks like isn't as important as what it does. An antioxidant keeps you healthy and young! Any choice you make that creates an imbalance--too much exercise and not enough rest, not enough sleep, an imbalanced diet, poor stress management--puts you at risk of antioxidant deficiency. If you're not making good lifestyle choices and assuming a supplement will absorb the imbalance, you're putting yourself at even greater risk. Be sure your diet has a lot of variety and color.

Even better, apply that mentality to the rest of your life.
--Create a social support network with a variety of personalities that encourage the best in you to come out, and who accept you for who you are without unrealistic expectations.
--Participate in a few different physical activities that allow muscles to rest while others work.
--Do things that make you laugh! (Yes, in a way, your favorite corny movie is an antioxidant!)
--Do something creative.

There are many kinds of antioxidants that have nothing to do with nutrition. Be sure your choices add up to move you in the direction of capitalizing on them, rather than putting you in a position where you need to supplement to reverse damage that didn't need to be done.

OK, good friend, I hope I answered your question and you made it to the end of this blog post without rolling those eyes again!

Most of you know that your PCOS is an inflammatory disorder. But if someone asked you what that meant, would you be able to explain it? I've found that it's a pretty meaningless and misleading term to most people. So I like to use a visual. This visual has had such a profound impact on some of my clients that they've printed it out and they hang it on their computers or other prominent place to graphically remind them of the importance of making proactive choices.

Inflammation is a misleading term because most people, when they hear it, tend to think of swelling, as you might experience if you sprain your ankle. In the case of inflammatory disease, it's really more oxidation that we're talking about. (Hence the focus on antioxidants by the supplement industry).

But even then…what is oxidation? It is the metabolic effect of oxygen being broken down. Outside of your body, the easiest illustration I've come up with is rust. When metal reacts with oxygen, and an oxidative process occurs, rust is the result.

It's no different in your body. An inflammatory, or oxidative process, is essentially the rusting out and deterioration of your tissues. It happens when the balance between processes that oxidize outweigh those that do repair work.

One of the most important places where this oxidation has effect is in your brain and nervous system. Oxidative processes are known to destroy neurons! For example, depression, another inflammatory disorder and one which commonly co-exists with PCOS, is known to destroy neurons in the hippocampus, the brain's memory center. And as many of you know, loss of memory, concentration…brain fog…are common side effects of PCOS.

Take a look at this photo. If the balance in your own body is tipped toward inflammation, it's literally like your brain and nervous system are rusting out. Yes, this is your brain on inflammation.

Your job is to reverse that process.

And it can be reversed! Studies also show that the hippocampus rebuilds those lost neurons as an indication of resolving depression.

What to do?

1. Remember that the substance that the brain needs in order to rebuild neurons is DHA. It's not sugar, it's not flax, it's not a vitamin or mineral. It's DHA, the fish oil that is found in fish and marine algae. Dr. Artemis Simopolous, omega-3 expert, has written that treating depression with DHA requires a dose of about 1000 mg per day. That is about 4 times what is recommended on the bottles of most supplements, and eating fish a few times a week is far below that. If you really want to experience the benefits of omega-3's, you likely need to up your dose.

2. You need to remember to take your fish oil! I know, it sounds funny, that in order to improve your memory you need to remember to use the thing that improves your memory…but that's one of the biggest barriers I've seen to PCOS success…consistency. If you cannot put your fish oil next to your milk in the refrigerator, or remember to take it when brushing your teeth, program your computer or smart phone to remind you to do so. I cannot reinforce the importance of consistency.

3. Slow down the rusting out process. Anything that raises metabolism, speeds up the rusting out process. That means extra stress. Sleep deprivation. Diet excesses. Dietary deficiencies. Too much exercise.

4. Eat a variety of foods from a variety of food groups. There are so many antioxidants available to you, none of them is the be-all-end-all…you need to mix it up so you get the most opportunity to benefit from the entire palette.

My hope is that now that you've seen what inflammation is, you will understand why it is so important to take action and do the repair work, then rust-proof yourself against further damage.

My post a few days ago about the effects of PCOS on the brain seems to have created some discomfort. We lost a few Facebook fans, and those who did respond, said that learning that PCOS was taking its toll on brain tissue and function was somewhat depressing to take. Theories of behavioral change state that until you know a problem exists, you will not act to change. So while the news can be uncomfortable to live with, the good news is, now you know why you need to make changes. You can't talk yourself out of those changes by convincing yourself that you're at peace with your body type, or that maybe you can live without having a baby. You're fighting for your cognitive life, and only you can make the changes that can make a difference. Here is a list of things you can do to help preserve brain and nervous system function. 1. Get sleep. You may think it's a badge of honor to cut yourself short in the sleep department. But it takes its toll. It is when you sleep, that your brain cleans out all the crud from the day before…spit shining neurons, so to speak. If you go too long without sleep, it's like you're letting rust accumulate all throughout your brain. Make it a habit to get to bed at an hour that allows you to get at least 7 hours of sleep a night. 2. Reduce stress. Every little thought, behavior, chemical reaction, that gets you through a day, requires a series of neurons to coordinate that activity. Every time a neuron is asked to work, it uses glucose to do so. Every time a neuron burns a molecule of glucose, it uses oxygen to do so. More neurons = more glucose = more oxidation. Make it a priority to give up the small stuff…and if you can't completely give it up…learn how not to sweat it so much. 3. Manage mental health issues. Most mental health diagnoses affecting PCOS (anxiety, bipolar disorder, PTSD, OCD, ADHD), involve processes that overwork the brain and nervous system. People with these disorders are fairly high energy, and that means they are using more neurons, more often, with far more intensity, than people who don't have to live with these conditions. Get counseling. If you need medication, take it. Health means MENTAL as well as PHYSICAL conditioning. Take it seriously. Do what you need to do. Slow down those neurons in any (legal) way available to you. 4. Exercise. Research is showing that regular physical activity slows down the development of brain diseases like Alzheimer's and helps to maintain brain tissue. How many times have you struggled with a problem at your desk, put it down, walked over to the post office, and had an inspiration while moving your body? Muscles and neurons are best friends. Be sure to give them plenty of play dates.

5. Eat less carbohydrate. Because your brain uses glucose, and because it's going to want more glucose when it is stressed, you're going to want to eat more carbs when under pressure. Remember what I said in number 2. The more carbs you eat, the more oxidative stress you impose on your brain. The more easily your brain rusts out and breaks down. I want you to think of this picture every time from this point forward you see a donut, order of french fries, or bottle of soda. Look less appetizing? Good. That was my point. 6. Eat antioxidants Antioxidants, those chemicals with the funny names nutrition experts love to impress people with in their blogs…hate oxidation. Eat them. Don't worry if you can pronounce their names, just know if the food in your hand (1) doesn't have an ingredient label, (2) has color, (3) and rots if left too long in your fridge, it's good for you. Put it on your plate and into your body. 7. Use fish oil. Fifteen percent of the dry weight of a healthy human brain is DHA, one of the primary omega-3's found in fish oil. It has to be fish, it can't be nuts, or flax, or greens. Eat the fish or take the capsules. I don't care if they come up a little bit. You have a choice…burps or brains. Just do it. 8. Reduce omega-6's. All those oils beginning with the letters"s" and"c"…break down brain tissue. Read labels. Get them out of your diet. Two exceptions. Organic canola is fine and coconut oil is fine, provided you're not eating it by the tablespoonful. 9. Yoga. Yoga tones the nervous system. It chills you out. It improves circulation in your spinal column. It improves your flexibility. It helps to manage mental health issues. It pretty much takes items 1 through 8 and makes them work even more effectively for you. It's worth the time. 10. Cut the high-fructose corn syrup. Recent research suggests that HFCS affects memory. Get it out of your diet!

I nagged you about fish oil a couple of days ago. Here's why.

One of the places where inflammation, the underlying cause for PCOS, does its worst damage, is the brain. It destroys neurons. Wondering where your motivation, your memory, your focus and concentration went? Out the door with inflammation.

Think about a piece of rusted out metal. That's the result of oxidation. Inflammation is the process that is trying to repair oxidation. But if you're burning through brain cells faster than you can repair them, you create holes. They've even shown it on brain scans. Where depression exists, (and depression is the result of so many brain cells being scavenged that the brain is literally moving in slow motion), there is inflammation.

There is one, and only one chemical known to man that can repair those holes. That chemical is docosahexaenoic acid (DHA), or one of the two things you get when you take fish oil. If you're vegan, you can get it in marine algae. If you've ever been vegan at any time in your life, or you hate or are allergic to fish, chances are it's a major factor in your PCOS. You can't repair your brain holes, and if you have holes in your brain, your brain can't regulate your hormones.

It is that simple. Really.

I had a client once who said to me,"This fish oil stuff works wonders. That is, when I remember to take it."

I don't care what you have to do — program your smart phone, post it note your computer monitor, ask your spouse to nag you — take fish oil.

The dose you're going to need is higher than what's recommended on the bottle. You're going to need 1000 mg, or 1 gram, of DHA per day. Not 1000 mg of total fish oil, of DHA. It's about 4 times what you see on many bottles.

Oh, and just so you know. That repairs the damage, but it doesn't protect you from new damage. For that part, you're going to have to change your eating and lifestyle. It really isn't going to work to take a ton of fish oil with the belief that it's cancelling out the damage done by that donut, by not working out, or not getting to bed on time.

I have clients who keep a rusty can next to their computer. It's a reminder. For some reason, when they hear that this PCOS thing is totally messing with their BRAINS — it gets their attention. If that's what you need to do, go find a rusty can. Yup, that could be your brain if you don't start getting that fish oil.

It's the first, most crucial step in the road to balancing your hormones. It's simple. And if you go to Costco, it's not really all that expensive.

Just do it. You'll be amazed at how quickly you start to notice little signs that inflammation is peeling away.

Over the past few years, oxygen facials have gained popularity, particularly with celebrities, as the path to more youthful skin. In a nutshell, these facials entail forcing oxygen that contains skin-healthy nutrients using compressed air.

When I first heard of these facials, working so much in the area of antioxidants, free radicals, and inflammation, which all accelerate the aging process, I couldn't help but wonder what adding all of that oxygen might have the potential to do. (There is a reason oxygen and oxidize sound so similar…oxidation is the damage done to tissues when deteriorating oxygen molecules are allowed to run loose in the body.)

My concern with this procedure has always been that since oxygen is natural, and we need it to survive, that people would buy these facials not understanding that too much oxygen may actually be harmful.

My second thought was that the force of the compressed air, applied continuously over time, may actually do more damage to fragile facial tissue, than the potential help all of the compounds it delivers, might provide.

The procedure has not been FDA-tested, so no one really knows for sure. So because there is immediate effect, and no one is going to report negative effects of such a profitable procedure unless legally required to, it's a very popular service in high-end beauty salons.

These are not inexpensive treatments, either. One California salon, on its website, advertises this service at $250 a visit. And since the recommended protocol is once a week for 6 weeks, then once a month thereafter, the first year of facials is going to cost $3600 annually.

Turns out, I wasn't the only skeptic. Apparently, the"proven effective" clinical testing often used to market these procedures refers to hyperbaric oxygen treatment, which these treatments are not (even though their marketing often says they are.)

In the words of beautymagonline.com, "why would we want to force the oxygen past the lipid bi-layers under pressure to an area where we really need to control any oxidation? As mentioned previously, oxygen as an energy providing fuel is delivered to the dermal cells via the microcirculation along with other vital nutrients. It is a critical balance. The fact that other topical oxygen bearing applications (such as hydrogen peroxide and oxygenated purified water) have lost favour with skin professionals due to free radical issues makes one wonder why less knowledgeable aestheticians and therapists have not made the connection between the similarity of the two modalities."

The FDA actually has a warning on its website stating that dispensing oxygen in medical concentrations, without a prescription, is not in FDA compliance.

That's the bad news. The good news? There is a new product on the market that delivers some of the same nutrients in a much kindler, gentler way…and it comes in chocolate cinnamon, chai, and vanilla flavors.: )

Nightly beauty by Beauty Foods, a nutricosmetic, that you can drink just before bedtime, contains BioCell Collagen, a patented combination of collagen and hyaluronic acid that has GRAS status (FDA Generally Regarded As Safe) actually has been clinically tested, and has been proven effective for enhancing skin quality. And not just for better, younger looking skin…for arthritis too! And daily use of this supplement, over a year, costs about $800 plus shipping.

So switching from oxygen facials to Nightly Beauty, alone, would save you about $2800.

Well, that is, if you don't calculate in the potential $325 you'll not be spending on Methotrexate (which has the nasty side effect of interfering with skin cell regeneration!)

Oh! And if the Alpha Calming waves and l-theanine help you to pitch your Ambien prescription as well, that is an extra ~ $230 you'll be saving.

I'm not even going to try to calculate the potential for improved insulin resistance and weight management, which happens in people who control their inflammation and stress, get adequate sleep, and consume a little bit of protein at bedtime.

All I know is, when I used the product for a month, I loved what it did for my skin, my eyes, my sleep…and I've really hated the washout period (not taking any of the product to see if the changes reverse). They did reverse, and now that I'm done being a guinea pig I'm ready to get back on the program.

Of course, we have to be sure the attorneys reading this post know we're not advising you to stop taking medications you've been prescribed. But when you look at a simple nutritional answer to a bunch of inflammation-related problems that the drug company would have you thinking is far more complicated — if it can't hurt and it may actually help, physically, mentally, and financially, why not try it and see if your physician can be convinced to write a few less scripts with your name on them?

If you'd like to try Beauty Foods for yourself, we're now offering it in our eMarket, where until Labor Day, 100% of proceeds go to our research institute, where we eventually can work to scientifically evaluate products just like this.

Not long ago Sasha Ottey of PCOS Challenge e-mailed me to see if I knew anything about"eggplant water". Seems it had been written up in the Los Angeles Times as a weight loss aid. It sounded strange, and she was looking to see if there was any scientific backing.

I was a little skeptical, but I did go to the National Library of Medicine database to see if anything existed. There was nothing about eggplant water specifically, but I did find a research abstract about the potential benefits of an eggplant-based diet. It appears that the antioxidants in eggplant are especially good for combating the types of degenerative processes common to insulin resistance.

Here it is, along with the reference. And below that, is a recipe for ratatouille, my favorite eggplant recipe. Enjoy!

National Diabetes Education Program of NIH, Mayo Clinic and American Diabetes Association recommend eggplant-based diet as a choice for management of type 2 diabetes. The rationale for this suggestion is the high fiber and low soluble carbohydrate content of eggplant. We propose that a more physiologically relevant explanation lies in the phenolic-linked antioxidant activity and alpha-glucosidase inhibitory potential of eggplant which could reduce hyperglycemia-induced pathogenesis. Results from this study indicate that phenolic-enriched extracts of eggplant with moderate free radical scavenging-linked antioxidant activity had high alpha-glucosidase inhibitory activity and in specific cases moderate to high angiotensin I-converting enzyme (ACE) inhibitory activity. Inhibition of these enzymes provide a strong biochemical basis for management of type 2 diabetes by controlling glucose absorption and reducing associated hypertension, respectively. This phenolic antioxidant-enriched dietary strategy also has the potential to reduce hyperglycemia-induced pathogenesis linked to cellular oxidation stress. These results provide strong rationale for further animal and clinical studies.

Kwon YI, Apostolidis E, Shetty K. In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension. Bioresour Technol. 2008 May;99(8):2981-8. Epub 2007 Aug 13.

Ratatouille

2 1/2 lb tomatoes (4 large)
8 large garlic cloves, thinly sliced
1 cup chopped fresh flat-leaf parsley
20 fresh basil leaves, torn in half
1 cup plus 2 tablespoons extra-virgin olive oil
2 lb eggplant, cut into 1-inch cubes
2 1/4 teaspoons salt
2 large onions (1 1/2 lb total), quartered lengthwise and thinly sliced crosswise
3 assorted bell peppers (green, red, and/or yellow; 1 1/2 lb total), cut into 1-inch pieces
4 medium zucchini (2 lb), quartered lengthwise and cut crosswise into 3/4-inch-thick pieces
1/2 teaspoon black pepper

Garnish: Parmigiano-Reggiano shavings and fresh basil

Cut an X in bottom of each tomato with a sharp paring knife and blanch together in a 4-quart pot of boiling water 1 minute. Transfer tomatoes with a slotted spoon to a cutting board and, when cool enough to handle, peel off skin, beginning from scored end, with paring knife.

Coarsely chop tomatoes and transfer to a 5-quart heavy pot with garlic, parsley, basil, and 1/3 cup oil. Simmer, partially covered, stirring occasionally, until tomatoes break down and sauce is slightly thickened, about 30 minutes.

While sauce is simmering, toss eggplant with 1/2 teaspoon salt in a large colander and let stand in sink 30 minutes.

Meanwhile, cook onions in 3 tablespoons oil with 1/4 teaspoon salt in a 12-inch heavy skillet over moderate heat, stirring occasionally, until softened, 10 to 12 minutes. Transfer onions with a slotted spoon to a large bowl, then add 3 tablespoons oil to skillet and cook bell peppers with 1/4 teaspoon salt over moderate heat, stirring occasionally, until softened, about 10 minutes. Transfer peppers with slotted spoon to bowl with onions. Add 3 tablespoons oil to skillet and cook zucchini with 1/4 teaspoon salt over moderate heat, stirring occasionally, until just tender, 6 to 8 minutes. Transfer zucchini with slotted spoon to bowl with other vegetables.

While zucchini are cooking, pat eggplant dry with paper towels. Add remaining oil (about 1/4 cup) to skillet and cook eggplant over moderate heat, stirring occasionally, until softened, 10 to12 minutes.

Add vegetables, remaining teaspoon salt, and black pepper to tomato sauce and simmer, covered, stirring occasionally, until vegetables are very tender, about 1 hour. Cool, uncovered, and serve warm or at room temperature.

I'm still working on learning to swim the butterfly stroke. Even though I've been swimming most of my life, something new about swimming occurred to me this past week. As calorically intense as swimming can be, I always leave the pool feeling invigorated. And at night…I fall right asleep and sleep through the night without issue.

I'm a pretty regular exerciser, but the nature of swimming, having to hold your breath, forces me to use my lungs differently than I do with any other exercise. I have to breathe more deeply into my lungs, and hold that air longer, than I do when I run or use exercise machines or rollerblade. My endurance with swimming is a little rusty, so, I have to stop and catch my breath which I don't have to do with any other exercise.

I think, because swimming is using my lungs in a more intensive way, it's better oxygenating my body. And that in turn leaves me feeling more energetic, since oxygen is necessary for healthy metabolism. And I sleep better at night when melatonin is triggered to come out and balance all that oxidation with restorative activity.

How well do you breathe? It is common, when stressed, to breathe more rapidly with shallower breaths. When you don't fully use your lungs, it's hard for adequate oxygen to get to your brain…and when your brain is stressed, it intensifies the feeling of anxiety, shortening breathing even more…thus starting a vicious cycle.

And…since the brain's main fuel is glucose, when you're not breathing adequately, you run the risk of having more sugar cravings.

When you're anxious, it is common to want to have an explanation for it. And the tendency is to blame it on something external, like your infertility, your weight, your appearance, your marriage, etc. It may be, at least some of the time, that your anxiety is directly related to how you're breathing.

Try this exercise the next time you're feeling anxious and see how you feel. Or…rather than waiting till you're anxious, try it several days in a row at a time of day you know you feel stressed (and hungry for carbs), such as when you get home from work just before dinner, and see if you start to notice a change in your mood and your appetite.

Lay down on your bed and place a book or pillow on your stomach. Make yourself breathe so that the object begins to move up and down. If you're breathing shallowly, with the top of your lungs, it will be hard to do this. So if the book doesn't move, focus on breathing into your belly button. Breathe like this for 20 breaths. Next time…30.

This is the kind of breathing you would learn to do in yoga class. It's exactly the kind of breathing I do in the middle of a counseling session or meeting when I feel stressed. I simply place a hand on my stomach to check if my breath is getting into the bottom of my lungs.

Of course, exercise is the ultimate way to do this kind of breathing. But it won't work for you in rush hour traffic, during your midterm, or when you're giving that sales presentation. Keep this technique handy in those situations, and exercise when you DO have time.

I'll be interested to hear from all of you about what you notice when you try this!

Oxidative stress, in the body, is much like rust on a car. It chips away at the integrity of body tissues, rendering them unavailable to function as they should. I don't have to tell you that…if you have PCOS and you have brain fog, it's a pretty huge red flag that you've got a degradative process going on. A recent study out of China has shown that oxidative stress is present in all women with PCOS, regardless of weight. Being lean does not protect you. This is extremely important to understand because the vast majority of advice I see given to women with PCOS, is simply to lose weight. Even though, if you are overweight, and you do lose weight, you may only be taking care of part of the picture. This Chinese study is important because it took the time to take out the weight issue, which can distract a lot of researchers from what may be the core issue. Forty-three obese women with PCOS and forty-two lean women with PCOS were evaluated for levels of several markers of inflammation and oxidation, including superoxide dismutase, 8-iso-prostaglandin F2alpha, and visfatin. For each of these compounds, regardless of weight, women with PCOS had higher levels of oxidative stress indicators than infertile women without PCOS. In the lean women, these metabolic disruptions were not as obvious, but they were still there. It looks like this is an additional layer of pathology that women with PCOS have, over and above infertility. And if all your physician or dietitian has done is suggest"lose weight"--it potentially could be part of the problem. I don't have to tell you that this can be an ominous task with PCOS, and women can often overexercise and over-restrict their diet in an effort to do so. Both of those choices can fuel the fire of oxidative stress and push your body in the wrong direction. See that Patriot missile in the photo? Oxidative stress works like that. It's like a million metabolic missiles floating all over your body, searching and destroying DNA, tissue, hormone function, pretty much everything. Losing weight the wrong way won't get you where you want to go. On the contrary, it only unleashes a whole new battalion of them. My message to you is this. Instead of beating yourself up in the gym with too much exercise and then punishing yourself when you get home with too little food, focus on ways to reduce that metabolic stress. You know we have four areas we like to see you focus on: (1) eating in a balanced fashion with plenty of fresh fruits and vegetables, (2) moving your body in a moderately active way, (3) getting enough sleep, and (4) managing your stress. It's not news on this blog. We just have some new friends in China who gave us some great research to reinforce that message. Liu J, Zhang D. [The role of oxidative stress in the pathogenesis of polycystic ovary syndrome]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2012 Mar;43(2):187-90.

We've all heard it--the stereotyped observation that obese people are lazy and stupid. People carrying more weight than the health charts have decided they should, are often discriminated against with regard to social popularity, salary, simple courtesy in retail stores. Weight and body image activists have tried to fight back with a"Health At Any Size" paradigm. Sometimes it seems as though it is taking hold. Most of the time it doesn't. If I didn't have a lot of compassion for people struggling with weight issues, I would not have devoted my career to nutrition, a specialty where these problems inevitably find themselves. That being said, there are characteristics of this population that can test my patience. When I find myself frustrated, I think about the"fat, lazy, and stupid" label that has stuck like glue and seems so impossible to change. Some of the situations I deal with consistently: 1. Lack of follow through on commitment to exercise. 2. Lack of follow through on keeping a diet diary. 3. Lack of follow through on scheduled appointments."Lazy" can be easy to replace those with, to the untrained eye. But I also see other things equally as frequently. 1. Extreme forgetfulness. One client was so forgetful he would forget he ate lunch and go fix himself a second, stopping only when he saw dishes in the sink to remind him he'd already eaten. 2. Pretty poor grammar and spelling. 3. Difficulty grasping concepts that are fairly easy for other audiences I teach to grasp. I have come to a place that lies halfway between Health at Any Size and Fat, Lazy, and Stupid. The behaviors are there, but I don't label them judgmentally. I view them as clinical symptoms. If you're having trouble remembering, spelling, adding, following instructions…you need to speak up. You need to let your caregivers know so they can start to associate neurocognitive issues with weight. You can't keep them to yourself because they are embarrassing. You're not stupid. Your nervous system is struggling. If you're too exhausted to exercise because you didn't sleep the night before, welcome to the club. A pretty high percentage of Americans are in the same boat. If your physician or personal trainer is so into their own physique that they can't hear that this is a problem for you…find another. A very high percentage of our clients discover that once they get the sleep corrected, they have all kinds of energy for exercise. Calling someone lazy and hoping to shame them into punishing themselves so you feel good about your reputation as a coach is not the answer. Fixing the sleep problem just might be. This was kind of a hard blog post to write. I am guessing some people got angry and quit reading before they got to this point because they are so adamant about their own viewpoint, or were so offended because they jumped to a conclusion that I was going to be condescending, they just checked out. If you didn't, and you're still with me, thank you. It is really hard to try and talk about these neurocognitive issues with a target audience who really just wants to lose weight or have a baby and doesn't want it to be any more complicated than that. Last Tuesday, the day I posted about brain oxidation, we lost a lot of Facebook fans. I may lose more with this post. That's ok. I want to find the real answer to the real problem with PCOS, not just tell you what you want to hear in the short term, leaving you set up for bigger problems awhile down the road. I can't wave a magic wand and make it all go away, but I can tell you I really want to know what is going on with you. We are putting a project together where members of our Institute will have an opportunity to share their symptoms in a collective database, so that we can look for relationships and correlations that may not be currently on research radars. If you're not part of the Institute, we do encourage you to share, honestly, with your caregivers, what is really going on. I believe we'll have a whole lot more success transitioning the"fat, lazy, stupid" stereoptype into a"hormone-imbalanced, exhausted, brain-fogged" clinical presentation, than we will in just making those horribly judgmental words go away. Besides, one way feels to me like it's just giving in and trying to believe you're healthy as you are. If that is truly how you felt, I'm guessing you wouldn't be sitting here on this blog. We look forward to working with you on unraveling this mystery and getting your life back on course.

Hello everyone,

It's great to be back with the new team of PCOS course graduates! I hope you enjoyed Susan Dopart's recipe and that other contributions will be educational and practically useful.

Today I wanted to share some recent findings about the effects of elevated glucose on a developing baby. If you have PCOS and you are pregnant, you are at risk for gestational diabetes. I realized while reading this study that rarely is the effect of hyperglycemia on the fetus ever discussed. You might hear that it can effect your weight and the baby's weight, but can it do anything else? Some researchers think so.

A group of chick eggs were injected with glucose. Significant changes were found in the babies that developed from those eggs, including:
--their own hyperglycemia
--elevated oxidative (degenerative) activity in body and brain tissue
--lower body weight
--lower brain weight
There also seems to be lower levels of DHA in babies exposed to hyperglycemia. This may be due to the elevated oxidative activity destroying any DHA that might be there.

You're likely aware that taking folate is pretty much an across the board recommendation to pregnant women. In this study, hyperglycemia seemed to induce a level of oxidation/inflammation that was not significantly helped with a folate supplement.

Bottom line, it's important to eat well not just to avoid weight gain or to keep your blood sugar low to keep your doctor and dietitian happy, but because your baby's brain and body depend on you to do so.

I did not write this post to scare you, I did it to make you aware. However, if you're feeling as if you now don't know what's right to eat, or you're trying and having a hard time, please take a look at the right hand of this blog screen. There is a whole list of professionals ready and waiting to help you figure it out.

Most of my clients express surprise that healthy eating includes as many tasty foods as it does. So before you write off a visit to the dietitian because you're afraid of what you WON'T be able to eat, consider that it may be your ticket to freedom and guilt relief to work with someone who can introduce you to the many foods that will BENEFIT you and baby!

Cole NW, Weaver KR, Walcher BN, Adams ZF, Miller RR Jr. Hyperglycemia-induced membrane lipid peroxidation and elevated homocysteine levels are poorly attenuated by exogenous folate in embryonic chick brains. Comp Biochem Physiol B Biochem Mol Biol. 2008 Jul;150(3):338-43.

Statistics say, a diagnosis of infertility is as stressful as a diagnosis of HIV or terminal cancer. So I'm always on the lookout for ways to help keep that stress from interfering with your hormone balance.

Recently, I've been researching L-theanine, a compound found in green tea, which is also used in supplement form. It's got some interesting benefits, including reduced blood pressure, reduced heart rate, antitumor activity, increased serotonin and dopamine levels in the hippocampus, hypothalamus, and striatum, neuroprotection, weight loss, stroke protection, improved learning and memory, reduced neuron excitability, reduced insulin concentration, suppressed food intake

Of course, the caffeine and polyphenols in green tea have enough benefit themselves that for the most part, I'd prefer to see green tea consumed whole instead of parsed into its separate parts. However, given the fact that this anxiety we see with our audience can stretch into the extreme zone, there may be benefit to L-theanine in addition to whole green tea in your daily program. I am also intrigued by the beneficial effects on learning and memory, given the number of you reporting the problems you're having in that department.

I'm running a little theanine experiment here with myself as the subject. Not that it's all that scientific, but I do like to test things I'm writing about, when I can, so I've got a personal as well as an evidence-based perspective. Stay tuned for some followup reports on how my study is coming along!

Yokogoshi H, Kato Y, Sagesaka YM, Takihara-Matsuura T, Kakuda T, Takeuchi N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci Biotechnol Biochem. 1995 Apr;59(4):615-8.

Sadzuka Y, Sugiyama T, Miyagishima A, Nozawa Y, Hirota S. The effects of theanine, as a novel biochemical modulator, on the antitumor activity of adriamycin. Cancer Lett. 1996 Aug 2;105(2):203-9.
Yokozawa T, Dong E. Influence of green tea and its three major components upon low-density lipoprotein oxidation. Exp Toxicol Pathol. 1997 Dec;49(5):329-35.

Yokogoshi H, Kobayashi M, Mochizuki M, Terashima T. Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem Res. 1998 May;23(5):667-73.

Terashima T, Takido J, Yokogoshi H. Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine. Biosci Biotechnol Biochem. 1999 Apr;63(4):615-8.

Kakuda T, Nozawa A, Unno T, Okamura N, Okai O. Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat. Biosci Biotechnol Biochem. 2000 Feb;64(2):287-93.

Kakuda T. Neuroprotective effects of the green tea components theanine and catechins. Biol Pharm Bull. 2002 Dec;25(12):1513-8.

Zheng G, Sayama K, Okubo T, Juneja LR, Oguni I. Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo. 2004 Jan-Feb;18(1):55-62.

Egashira N, Hayakawa K, Mishima K, Kimura H, Iwasaki K, Fujiwara M. Neuroprotective effect of gamma-glutamylethylamide (theanine) on cerebral infarction in mice. Neurosci Lett. 2004 Jun 3;363(1):58-61.

Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jan;74(1):39-45. Epub 2006 Aug 22.

Yamada T, Nishimura Y, Sakurai T, Terashima T, Okubo T, Juneja LR, Yokogoshi H. Administration of theanine, a unique amino acid in tea leaves, changed feeding-relating components in serum and feeding behavior in rats. Biosci Biotechnol Biochem. 2008 May;72(5):1352-5. Epub 2008 May 7.

It's getting hot outside, and that likely means you're getting thirsty.

A consistency I've noticed, in the years of examining food diaries, is how we seem to write off what we drink as far as its influence on our health. Calories, caffeine, sugar, even healthy ingredients such as antioxidants, get far less credit for what they do, than similar items that we chew! This can get us in trouble when the mercury climbs, and we start to bore of plain water. It's often not the food I try to tweak in a diet, but the juice, soda, or latte that's adding extra calories and promoting an overall imbalance.

If you look in the herbal tea section of your grocery store, you'll see lots of great alternatives. One of my personal favorites is hibiscus. It's not just a beautiful flower! It makes a delicious tea with quite a few health benefits:
--it has diuretic properties, which makes it perfect for PMS
--it is a mild antihypertensive
--one study suggested that it can help to reduce cholesterol and triglycerides
--it contains anthocyanins, those powerful antioxidants we tend to associate with blueberries
--it may have some anti-obesigenic properties

In my part of the country, especially in Spanish-speaking sections of town and REAL Mexican restaurants, we see a drink called Jamaica, which is a hibiscus-based beverage. The restaurant versions are likely too sweet to be consumed on a daily basis; here is a recipe from http://www.chow.com/, which you can probably make with far less sugar than the recipe calls for. I'd start with 1/3 of what is listed and gradually add until you like it.

Agua de Jamaica

3 quarts (12 cups) water

1 (1/2-inch) piece ginger, finely grated
1 1/2 cups dried Jamaica flowers (also known as hibiscus or flor de Jamaica)
1 1/2 cups granulated sugar
2 tablespoons freshly squeezed lime juice (from 1 large lime)

Combine water and ginger in a large pot and bring to a boil over high heat.

Remove from heat and stir in Jamaica flowers and sugar until sugar is dissolved. Let steep 10 minutes.

Strain through a chinois or fine mesh sieve into a large, heat-resistant bowl or pot. Stir in lime juice and set aside to cool. Refrigerate until ready to use. Serve over ice.

Gosain S, Ircchiaya R, Sharma PC, Thareja S, Kalra A, Deep A, Bhardwaj TR. Hypolipidemic effect of ethanolic extract from the leaves of Hibiscus sabdariffa L. in hyperlipidemic rats. Acta Pol Pharm. 2010 Mar-Apr;67(2):179-84.

McKay DL, Chen CY, Saltzman E, Blumberg JB. Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr. 2010 Feb;140(2):298-303. Epub 2009 Dec 16.

Alarcon-Aguilar FJ, Zamilpa A, Perez-Garcia MD, Almanza-Perez JC, Romero-Nuñez E, Campos-Sepulveda EA, Vazquez-Carrillo LI, Roman-Ramos R. Effect of Hibiscus sabdariffa on obesity in MSG mice. J Ethnopharmacol. 2007 Oct 8;114(1):66-71. Epub 2007 Jul 27.

Chang YC, Huang KX, Huang AC, Ho YC, Wang CJ. Hibiscus anthocyanins-rich extract inhibited LDL oxidation and oxLDL-mediated macrophages apoptosis. Food Chem Toxicol. 2006 Jul;44(7):1015-23. Epub 2006 Feb 13.

Yesterday I shared some great news from an Italian research group about myoinositol for improving fertility. In the process of corresponding, they sent me a series of articles from their lab. One of their most recent investigated the combination of myoinositol and melatonin in fertility treatment.

Here's how it looks like the story goes.

Ovulation is an inflammatory process Yes, the process of releasing an egg, and giving life, is pro-inflammatory. It takes a lot of energy to do this, and as that energy is metabolized, it's oxidizing tissue around it.

Melatonin is one of the most powerful antioxidants we have You know, if you think about this the way Mother Nature does, it makes sense that we'd want to roll over and sleep all cuddled up after sex. It is her way of protecting that fragile egg from all of the stresses of the day.

The research I read yesterday was about INOFOLIC PLUS, an Italian proprietary blend of inositol, folic acid, and melatonin. Forty-six women who had previously undergone in-vitro fertilization (IVF) and failed, used this supplement daily for 3 months before undergoing another IVF procedure. They also continued to take INOFOLIC throughout the entire IVF cycle. This study, by the way, did NOT focus on women with PCOS, merely women who had failed IVF.

Here are some of the results of the second IVF in which the supplement was used:
--Higher number of embryo transfers
--Higher embryo quality
--Where all of the subjects had failed with their first IVF the first time, 13 (28%) became pregnant during the study, 4 miscarried.

What is remarkable about this study is that the average age of these women was 39 years, an age where fertility is starting to become difficult even without a diagnosis of infertility.

The supplement is not perfect, but it shows promise for helping women for whom other strategies have failed. It seems to be a great combination of compounds for peeling off the layers of inflammatory/oxidative damage have inflicted on reproductive systems…talking your ovaries down out of the tree, so to speak. What it seems to do, is both create a higher quality egg and then protect it from the ravages of oxidation long enough for it to meet a sperm, conceive, and create an embryo.

Ahhhhhh…just love the power we have within ourselves to create healing solutions!

As I mentioned yesterday, unfortunately, INOFOLIC is not available in the United States. However, there is an important bottom line message here that cannot be ignored.

When you're not eating enough antioxidants, not delegating, working too hard, not sleeping well, not managing your stress, the melatonin Mother Nature given you to protect your eggs, may likely be channeled into fighting other damages those lifestyle choices have promoted.

Not trying to shake the eFinger at you here, it's just becoming apparent from listening to so many of your stories that when we don't take good care of ourselves, the effects can stick around for a very long time. And when we do things in an effort to eat well but don't do our homework first (such as eating vegan but not making sure all nutrients are still adequate in the diet or panicking and going on a crash diet in order to get pregnant, or overexercising as the only way to manage stress), they can hurt us in the long run.

If you start to think about your choices as"What can I do to not unnecessarily use my own antioxidant power so it can be there for that egg?"…perhaps making some of those choices you've been reluctant to take on, might become easier to embrace.

Unfer V, Raffone E, Rizzo P, Buffo S. Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte
quality: a prospective, longitudinal, cohort study. Gynecol Endocrinol. 2011 Apr 5. [Epub ahead of print]

VITTORIO UNFER1, EMANUELA RAFFONE2, PIERO RIZZO2, & SILVIA BUFFO3